Our Mr Levi, 105lb Cane Corso, has been using Fido Flora and the Liver Detox together for about 6 weeks. We have doubled his dose of Fido Flora to twice aday to get on top of his hot spot issue. We did this alondside his second bottle of Liver Detox. He will stay on the Liver Detox for 3 months, and in month 3 we will drop his Fido Flora back down to the recomended once a day. He no longer has any hotspots, he is not chewing or scratching at all. This has been costly but has been well worth every penny to see our Mr Levi comfortable again. Thank-you Adored Beast.